San Francisco 49ers vs Green Bay Packers Divisional Pick

Our San Francisco vs Green Bay prediction is for the first NFC Divisional Round game of the 2022 playoffs. It will kick off at 8:15 pm ET on Saturday, January 22, 2022. In this NFL contest, the Packers are favored by -5.5 (-102). The underdog Niners are listed at +5.5 (-109). The total is 47.0 with the over at -113 and under at -102.

The San Francisco 49ers (10-7 Overall, 6-3 Away) finished third in the NFC West. In their final five games, SF went 4-1. In the Wildcard Round, the 49ers beat Dallas 23-17. The Green Bay Packers (13-4 Overall, 8-0 Home) won four of their last five games, thus taking down the NFC North. They also posted the best record in the NFC, which earned them a bye. During the regular season, these two teams met in Week 3 in San Francisco. Green Bay won that game 30-28.

This NFC Divisional contest will be played at Lambeau Field in Green Bay, WI. The weather will be cloudy with winds from the W at 7 mph and gusts at 12 mph. Temperatures will be 12-13 degrees with a windchill of 5 degrees. The game will be on FOX.

San Francisco vs Green Bay Prediction – Keys

In the regular season, our San Francisco vs Green Bay prediction notes the Packers averaged 26.5 PPG while the 49ers were good for 25.1. Total offensive yards slightly favor SF, 375.7-365.6. Both teams are close in rushing and passing yards per game with the Packers recording a few more air yards and the Niners a few more yards on the ground. Green Bay is a bit better in pass completion percentage (67.8-66.7), while both sides have allowed 33 sacks each. Picks given up stand at seven for the Packers and 14 for SF. Green Bay has 39 passing TDs, while the 49ers total 26. However, the Niners have 22 ground scores. On the other hand, the Packers have rushed for 13 touchdowns.

Defense

The Packers are permitting opponents 21.8 PPG, while the SF is allowing 21.5. The Niner D is allowing just 206.5 air ground and 103.5 ground YPG. The Packer defense is permitting a tad more, as opponents are averaging 219.1 passing and 109.1 rushing YPG. SF leads in sacks (49-38), while GB is better in interceptions (18-9). Finally, San Fran has allowed fewer TDs in the air (25-31) and Green Bay few touchdowns on the ground (13-17).

49ers - Players

In 15 games this season, Jimmy Garoppolo has thrown for 3,810 yards and 20 TDs, completing 68.3 percent of his passes. He’s tossed 12 picks and been sacked 29 times. Along with being one of SF’s top pass catchers, wideout Deebo Samuel is also a dangerous running back. His versatility gives the Niners an unpredictable weapon that is tough to defend against. The receiving unit, which is especially deep and productive, includes tight end George Kittle and wideout Brandon Aiyuk. In just 11 games, running back Elijah Mitchell has gained over 900 yards and scored five times.

On defense, end Nick Bosa, who has 15.5 sacks, 21 TFL, and 4 FF, leads the San Francisco frontline. Although the Niners have just nine picks, they have recorded 55 PD, 22 FF, and 11 FR. Plus, the team has tallied an impressive 98 TFL.

Packers - Players

QB Aaron Rodgers is at the top of his game. Along with completing 68.9 percent of his passes, he’s tossed 37 TDs and just four picks. Plus, Rodgers is the best misdirection quarterback in the league, often faking out opponent defenses as well as network cameramen and analysts. Aiding in those fakes are the Packer running backs. Rushers Aaron Jones and AJ Dillon, who have four and five rushing TD respectively and 800 yards each, have caught six and two TD passes respectively. Plus, the wideouts are four deep and have totaled 27 scores. Davante Adams leads the group with 123 receptions, 1,553 yards, and 11 TDs.

On defense, LB De'Vondre Campbell (102 TKLs, 44 ASTs,5 PD, 2 INTs, 2 FF, 1 FR) leads the team with 146 total tackles. He also has two sacks and six TFL. LBs Rashan Gary (9.5, 6 TFL, 2 FF, 1 FR) and Preston Smith (9 SCKs, 9 TFL, 2 FF, 1 FR) are solid pass rushers and run stoppers. Cornerback Rasul Douglas (13 PD, 5 INTs) is the lynchpin for the secondary. The Green Bay defense has scored three times while defending 74 passes and recording 54 TFL.

San Francisco vs Green Bay Prediction - Spread & Totals

In our NFC San Francisco vs Green Bay prediction, we see the Packers as having a clear advantage. Like Tennessee in the AFC, the Pack is rested. Plus, Green Bay is undefeated at home this season, and Rodgers performs well in cold weather. When the temperature drops, Garoppolo has always struggled. At the end of the season, the Niners came on strong. Although they beat Dallas in the Wildcard game, the Cowboys, in many ways, beat themselves. We don’t expect to see the Packers implode in the same manner. We like Rodgers, who is hungry for a Super Bowl and has been playing near flawless football. Plus, Green Bay’s defense has three scores. The Niner D has none. We’re going with Green Bay at -5.5 (-102) and the over at 47.0 (-113).

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Summary – San Francisco 49ers vs Green Bay Packers Divisional Pick:

  • Point Spread Pick – Green Bay Packers at -5.5 (-102)

  • Totals Pick - Over 47.0 (-113)

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